PSA Blood Test (Prostate Specific Antigen)
A PSA test measures the amount of prostate specific antigen in your blood as a way to test for prostate cancer.
Our PSA Blood test is a quick and easy way to test for prostate cancer. We check your PSA levels with our at home finger-prick blood test to understand your risk of prostate cancer.
- Results and doctor's report in 2 days or less
- Free, next-working day delivery
- Testing for Prostate Specific Antigen
£55.00
Personalise your PSA Blood Test (Prostate Specific Antigen)
You can choose how you'd like to collect your blood sample. You may also want to add to your test panel depending on your age, sex and any symptoms.
Finger-prick blood collection
Use our simple kit to collect a blood sample from your finger at home.
Arrange for a venous blood draw yourself
Visit a clinic to have your blood taken
Dr Alasdair Scott
gut doctor, PhD and our Science Director
What you need to know about our PSA Blood Test (Prostate Specific Antigen)
Dr Alasdair Scott
gut doctor, PhD and our Science Director
Prostate cancer often doesn't cause any symptoms and the commonest way to pick it up is actually following a PSA blood test.
Regular PSA testing has been shown to pick up more cases of prostate cancer, increases your chances of picking up prostate cancer before it has spread and reduces the chance of dying from prostate cancer by about 30%ref.
Guidelines support PSA testing from age 45 to understand your baseline risk of prostate cancer and to guide how regularly you should consider testing. Men at higher risk - of black ethnic origin or with a family history of prostate cancer for example - should start testing earlier, from age 40.
PSA testing is the first, crucial step in the pathway of prostate cancer diagnosis and management and taking it puts you firmly in the driving seat.
What do the PSA test results mean?
Your PSA level needs to be interpreted in the context of your age because PSA naturally goes up as you get older due to the prostate increasing in size. The National Institute of Clinical Excellence (NICE) have suggested PSA thresholds for specific ages to trigger further investigation of the prostate (e.g. with an MRI scan).
| Age | PSA Threshold (μg/L) |
| 40 - 49 | >2.5 |
| 50 - 59 | >3.5 |
| 60 - 69 | >4.5 |
| 70 - 79 | >6.5 |
| Over 79 | Use clinical judgement |
However, other guidelines recommend that all men with a PSA above 3μg/L undergo further investigations. We suggest that anyone with a PSA level over 2.5μg/L discuss this with their doctor.
A high PSA level doesn't mean you have prostate cancer but it does make prostate cancer more likely and you'll generally be advised to have a scan of the prostate to investigate further.
How accurate is a PSA test?
Remember that the PSA test is not meant to be a test to identify prostate cancer. It is a test to assess your risk of having prostate cancer. Your risk of prostate cancer will depend on how high your PSA level is.
- If your PSA level is between 4 - 10 μg/L, your risk of prostate cancer is about 25%.
- If your PSA level is over 10 μg/L, your risk of prostate cancer is over 50%.
However, it's important to bear in mind that about 1 in 7 men can have a normal PSA level and later be diagnosed with prostate cancer. This is why it's so important for men to monitor their PSA level regularly rather than just as a one-off.
5α-reductase inhibitors can falsely lower PSA levels so you need to adjust your result (doubling your PSA) if you take this medication.
What's tested in your PSA Blood Test (Prostate Specific Antigen)?
Our PSA test checks for prostate specific antigen levels in your blood. High PSA levels can be a sign of prostate cancer and should be followed up with a prostate scan.
In addition to testing your PSA level, we'll also test your free PSA level and Free-to-Total PSA ratio if your PSA level is borderline high, at no extra cost. These markers give you more information on your prostate cancer risk.
- Prostate specific antigen (PSA)
Your PSA level can help you understand your risk of prostate cancer and guide further testing.
- Free PSA
If your PSA level is between 2.0 - 10μg/L we'll check your free PSA level to get more information on your prostate cancer risk
- Free PSA to Total PSA ratio
If your PSA level is between 2.0 - 10μg/L we'll calculate your free to total PSA ratio to help guide further actions by your doctor.
If you're under 40 years of age your risk of prostate cancer is extremely low and we don't have any research to suggest a benefit in terms of predicting your future risk of prostate cancer when testing at this age.
In order to make your PSA test as accurate as possible, it’s important to prepare for it by:
- making sure you’ve not had a urinary tract infection in the previous 6 weeks
- avoiding ejaculation for 2 two days beforehand
- avoiding vigorous exercise, particularly cycling, for the previous 2 days
- waiting at least 6 weeks after a prostate biopsy or cystoscopy before testing
How often you should take a PSA test depends on your last PSA level and if you're at higher risk of prostate cancer (black ethnicity or family history of prostate cancer for example).
- If your PSA level is 1-3 μg/L or you're at higher risk of prostate cancer, guidelines recommend checking your PSA every year.
- If your PSA level is less than 1 μg/L and you're not at higher risk of prostate cancer, then guidelines recommend checking your PSA level every 2 years.
PSA velocity is a measure of how your PSA level is changing over time. Even within the normal range, a high PSA velocity can be a sign of prostate cancer. A velocity over 0.75μg/L per year or >25% is considered suspicious and should prompt investigation This is why it's important to check your PSA regularly.
Total PSA actually includes two different forms of PSA. PSA can be bound to other proteins in the blood or it can be ‘free’, meaning that it’s not bound to other proteins.
Free PSA levels are often higher with non-cancerous conditions of the prostate and lower in those with prostate cancer.
We routinely measure free PSA and the ratio of free to total PSA in people who have a PSA of between 2.5 - 10μg/L because it provides more information on prostate cancer risk.
- If your PSA level is 2.5 - 4 μg/L then a normal Free:Total PSA ratio is >0.19.
- If your PSA level is 4 - 10 μg/L then a normal Free:Total PSA ratio is >0. If your Free:Total PSA ratio is above these cut-offs then it makes prostate cancer more likely compared to a ratio below the thresholds.
People assigned male at birth will have a prostate and this is not removed during gender-affirming surgery. Therefore trans women are at risk of prostate cancer. However, testosterone lowering therapy can reduce the risk of prostate cancer but it can also falsely lower PSA levels, making them difficult to interpret. Prostate Cancer UK has useful information about the risk of prostate cancer as a trans woman.
Get updates on how to live more healthy years
Selph Ltd, Reg. No. 12169438
124 City Road, London, EC1V 2NX
